H318: indicazione di pericolo CLP

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7 min di letturaAggiornato il 08/07/2026clp

L'indicazione di pericolo H318 è uno dei codici H del Regolamento CLP (CE) n. 1272/2008: «Provoca gravi lesioni oculari.». Nel Regolamento CLP il codice H318 è l'indicazione di pericolo prevista per la classe Gravi lesioni oculari/irritazione oculare, categoria 1 (Eye Dam. 1) (Allegato I; elenco nell'Allegato III, parte 1). In questa pagina trovi il testo ufficiale, a quale classe è collegata, il pittogramma tipico e un elenco di sostanze con classificazione armonizzata che la riportano.

Che cos'è l'indicazione H318

Testo ufficiale dell'indicazione H318 (Allegato III del CLP): «Provoca gravi lesioni oculari.»

Le indicazioni di pericolo (codici H) descrivono la natura e, se del caso, il grado del pericolo di una sostanza o miscela. Il testo ufficiale di ogni codice è stabilito dall'Allegato III del CLP, uguale per tutte le sostanze, e in etichetta va riportato per esteso. Il codice H318 si riconosce dalla classe di pericolo a cui è associato e dal pittogramma con cui compare.

Classe di pericolo associata a H318

Nel Regolamento CLP il codice H318 è l'indicazione di pericolo prevista per la classe Gravi lesioni oculari/irritazione oculare, categoria 1 (Eye Dam. 1) (Allegato I; elenco nell'Allegato III, parte 1).

Codice H	Classe e categorie (CLP)	Codici	Tipo di pericolo
H318	Gravi lesioni oculari/irritazione oculare, categoria 1	Eye Dam. 1	salute

Approfondisci la classe collegata: Gravi lesioni oculari (CLP).

Pittogramma tipico

Per la classificazione indicata sopra, l'Allegato I del CLP (tabella 3.3.5) prevede per H318 il pittogramma:

GHS05 – Corrosione (Allegato V, punto 2.2)

Eventuali altri pittogrammi presenti in etichetta derivano dalle altre classificazioni della sostanza o miscela.

Sostanze con indicazione H318

Esempi di sostanze la cui classificazione armonizzata include H318. Apri la scheda per tutti i codici di classe, le indicazioni H e i pittogrammi:

( N -benzyl- N -ethyl)amino-3-hydroxyacetophenone hy
( S )-α-(acetylthio)benzenepropanoic acid
( Z )-1-benzo[ b ]thien-2-ylethanone oxime hydrochlo
((4-phenylbutyl)hydroxyphosphoryl)acetic acid
(-)- trans -4-(4'-fluorophenyl)-3-hydroxymethyl- N –
(1 R ,4 S )-2-azabicyclo[2.2.1]hept-5-en-3-one
(2-(1,3-dioxolan-2-yl)ethyl)triphenylphosphonium bro
(3'-carboxymethyl-5-(2-(3-ethyl-3 H -benzothiazol-2-
(4-aminophenyl)- N -methylmethylensulfonamide hydroc
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-n
(9 S )-9-amino-9-deoxyerythromycin
(ethyl-3-oxobutanoato- O '1, O '3)(2-dimethylaminoet
(±)- trans -4-(4-fluorophenyl)-3-hydroxymethyl- N -m
(η-cumene)-(η-cyclopentadienyl)iron(II) hexafluoroan
1,2,3,6-tetrahydrophthalic anhydride
1,2-benzisothiazol-3(2H)-one
1,2-dimethylimidazole
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1 H
1,3,5-tris-[(2 S and 2 R )-2,3-epoxypropyl]-1,3,5-tr
1,3-bis(3-methyl-2,5-dioxo-1 H -pyrrolinylmethyl)ben
1,3-bis(vinylsulfonylacetamido)propane
1,4,5,8-tetraaminoanthra quinone
1,4,7,10-tetraazacyclododecane disulfate
1,4-dihydroxybenzene
1- tert -butoxypropan-2-ol
1-((2-quinolinyl-carbonyl)oxy)-2,5-pyrrolidinedione
1-(1-naphthylmethyl)quinolinium chloride
1-(2-(ethyl(4-(4-(4-(4-(ethyl(2-pyridinoethyl)amino)
1-(3-(4-fluorophenoxy)propyl)3-methoxy-4-piperidinon
1-[3-[4-((heptadecafluorononyl)oxy)-benzamido]propyl
1-bromo-3,4,5-trifluorobenzene
1-chloro- N , N -diethyl-1,1-diphenyl-1-(phenylmethy
1-naphtol
1-vinyl-2-pyrrolidone
2 S -isopropyl-5 R -methyl-1 R -cyclohexyl 2,2-dihyd
2,2'-iminodiethanol
2,2-bis(hydroxymethyl)butanoic acid
2,2-ethylmethylthiazolidine
2,3,4-trifluoroaniline
2,3,5,6-tetrafluorobenzoic acid
2,3,5,6-tetrahydro-2-methyl-2 H -cyclopenta[ d ]-1,2
2,3,5-trimethylhydroquinone
2,3-dichloro-5-trifluoromethyl- pyridine
2,3-dichloropropene
2,3-epoxypropyl methacrylate
2,4-bis[2,2'-[2-( N, N -dimethylamino)ethyloxycarbon
2,4-D (ISO)
2,4-dichloro-3-ethyl-6-nitrophenol
2,4-difluoro-α-(1 H -1,2,4-triazol-1-yl)acetophenone
2,5-dibutoxy-4-(morpholin-4-yl)benzenediazonium 4-me
2,6-bis-(2-(4-(4-amino-phenylamino)-phenylazo)-1,3-d
2-((4-amino-2-nitrophenyl)amino)benzoic acid
2-(2,4-dichlorophenyl)-1-(1 H —1,2,4-triazol-1-yl)pe
2-(2-(2-hydroxyethoxy)ethyl)-2-aza-bicyclo[2.2.1]hep
2-(2-hexyloxyethoxy)ethanol
2-(3-iodoprop-2-yn-1-yloxy)ethyl phenylcarbamate
2-(4- tert -butylphenyl)ethanol
2-(decylthio)ethylammonium chloride
2-(isocyanatosulfonylmethyl)benzoic acid methyl este
2-(octylthio)ethanol
2-[2-(2-butoxyethoxy)ethoxy]ethanol
2-[[4[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-
2-alkoyloxyethyl hydrogen maleate, where alkoyl repr
2-chloro-4,5-difluorobenzoic acid
2-chloromethyl-3,4-dimethoxypyridinium chloride
2-hydroxy-3-(2-ethyl-4-methylimidazoyl)propyl neodec
2-hydroxy-3-[(2-hydroxyethyl)-[2-(1-oxotetradecyl)am
2-hydroxymethyl-9-methyl-6-(1-methylethyl)-1,4-dioxa
2-isopropyl-4-( N -methyl)aminomethylthiazole
2-methoxypropanol
2-methyl-5-(1,1,3,3-tetramethylbutyl)hydroquinone
2-methylaziridine
2-methylpropan-1-ol
2-phenoxyethanol
2-{4-(2-ammoniopropylamino)-6-[4-hydroxy-3-(5-methyl
3(or 5)-(4-( N -benzyl- N -ethylamino)-2-methylpheny
3,4-dichloroaniline
3-(2-ethylhexyloxy)propane-1,2-diol
3-(3-methylpent-3-yl)isoxazol-5- ylamine
3-amino-4-hydroxy- N -(2-methoxyethyl)-benzenesulfon
3-aminomethyl-3,5,5-trimethylcyclohexylamine
3-azidosulfonylbenzoic acid
4,4'-bis(dimethylamino)benzophenone
4,4'-ethylidenediphenyl dicyanate
4,4'-isopropylidenediphenol
4,4'-thiodi- o -cresol
4-(1-oxo-2-propenyl)-morpholine
4-(2-chloro-4-trifluoromethyl)phenoxy-2-fluoroanilin
4-[3-(diethoxymethylsilylpropoxy)-2,2,6,6-tetramethy
4-[4-amino-5-hydroxy-3-(4-(2-sulfoxyethylsulfonyl)ph
4-cyclohexyl-2-methyl-2-butanol
4-dimethylaminobenzenediazonium 3-carboxy-4-hydroxyb
4-methyl-N-(methylsulfonyl)benzenesulfonamide
4-nitrosophenol
5,6-dihydroxyindole
5- tert -butyl-3-isoxazolylamine hydrochloride
5-acetyl-3-amino-10,11-dihydro-5 H -dibenz[ b, f ]az
5-thiazolylmethanol
5-{4-[5-amino-2-[4-(2-sulfoxyethylsulfonyl)phenylazo
6-(nonylamino)-6-oxo-peroxyhexanoic acid
6-(phthalimido)peroxyhexanoic acid
6-fluoro-2-methyl-3-(4-methylthiobenzyl)indene
6-hydroxyindole
8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride
[ R -( R *, S *)]-[[2-methyl-1-(1-oxopropoxy)propoxy
A reaction mass of: (1,3-dioxo-2 H -benz(de)isoquino
acifluorfen (ISO)
acrylonitrile
allyl glycidyl ether
azocyclotin (ISO)
behenamidopropyl-dimethyl-(dihydroxypropyl) ammonium
benzene-1,2,4-tricarboxylic acid 1,2-anhydride
benzene-1,2:4,5-tetracarboxylic dianhydride
benzyldimethyloctadecylammonium 3-nitrobenzenesulfon
biphenyl-2-ol
bis( N -(7-hydroxy-8-methyl-5-phenylphenazin-3-ylide
bis(3-(trimethoxysilyl)propyl)amine
bis(dimethyl-(2-hydroxyethyl)ammonium) 1,2-ethanediy
bis[(1-methylimidazol)-(2-ethyl-hexanoate)], zinc co
bis[[2,2',2''-nitrilotris-[ethanolato]]-1- N , O ]-b
bis[tributyl 4-(methylbenzyl)ammonium] 1,5-naphthale
bronopol (INN)
butan-1-ol
butanone oxime
C 12-14 – tert -alkyl ammonium 1-amino-9,10-dihydro-
C.I. Basic Violet 3
C.I. Basic Violet 3 with ≥ 0,1 % of Michler's ketone
calcium cyanamide
calcium phosphide
captan (ISO)
chlorocresol
chlorothalonil (ISO)
cis -1,2,3,6-tetrahydro-4-methylphthalic anhydride
clopyralid (ISO)
copper(II) methanesulfonate
crotonaldehyde
cyanamide
cyclohexane-1,2-dicarboxylic anhydride
cyclopentyl chloroformate
D, L-( N , N -diethyl-2-hydroxy-2-phenylacetamide)
dalapon
di- n -butylamine
di- tert -(C 12 – 14 )-alkylammonium 2-benzothiazoly
diamminediisocyanatozinc
diammonium hexachloroplatinate
diammonium tetrachloroplatinate
dibenzylphenylsulfonium hexafluoroantimonate
dibutyltin hydrogen borate
dicamba (ISO)
dichlorprop (ISO)
dichlorprop-P (ISO)
dicopper oxide
dicyclohexylcarbodiimide
dicyclopentyldimethoxysilane
dimethyldioctadecylammonium chloride
dipotassium hexachloroplatinate
dipotassium tetrachloroplatinate
disodium (3-methyl-4-(5-nitro-2-oxidophenylazo)-1-ph
disodium 1-amino-4-(4-benzenesulphonamido-3-sulphona
disodium 5-[5-[4-(5-chloro-2,6-difluoropyrimidin-4-y
disodium hexachloroplatinate
disodium tetrachloroplatinate
disul (ISO)
divanadyl pyrophosphate
DNOC (ISO)
E -ethyl-4-oxo-4-phenylcrotonate
ethyl 2-(3-nitrobenzylidene)acetoacetate
ethyl 2-(isocyanatosulfonyl)benzoate
ethyl 2-carboxy-3-(2-thienyl)propionate
ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate
ethyl lactate
ethylene oxide
exo -1-methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]h
fentin acetate (ISO)
fentin hydroxide (ISO)
formic acid … %
glyphosate (ISO)
guazatine (ISO)
hafnium tetra- n -butoxide
hexachloroplatinates with the exception of those spe
hexahydro-4-methylphthalic anhydride
hexasodium (di[ N -(3-(4-[5-(5-amino-3-methyl-1-phen
hexasodium tungstate hydrate
hydroxylamine … % [> 55 % in aqueous solution]
hymexazol (ISO)
imazalil (ISO)
lead(II) methanesulphonate
lithium 1-amino-4-(4-tert-butylanilino)anthraquinone
lithium sodium (4-((5-chloro-2-hydroxyphenyl)azo)-2,
magnesium bis(( R )-2-(2,4-dichlorophenoxy)propionat
main component 6 (isomer): asym. 1:2 Cr(III)-complex
malachite green hydrochloride
maleic anhydride
MCPA (ISO)
mecoprop (ISO)
mecoprop-P (ISO) [1] and its salts
metalaxyl- M (ISO)
methyl ( R )-2-(4-hydroxyphenoxy)propionate
methyl 2 R ,3 S -(-)-3-(4-methoxyphenyl)oxiranecarbo
methyl 4-bromomethyl-3-methoxybenzoate
methyl chloroacetate
methyl isocyanate
methyltriphenylphosphonium chloride
mono-2-[2-(4-dibenzo[b, f][1,4]thiazepin-11-yl)piper
mono-methylamine
mono[2-(dimethylamino)ethyl]monohydrogen-2-(hexadec-
N , N '-bis{6-chloro-4-[6-(4-vinylsulfonylphenylazo)
N -[2-hydroxy-3-(C 12-16 -alkyloxy)propyl]- N -methy
N -cyclohexyl- S, S -dioxo benzo[ b ]tiophene-2-carb
N -dodecyl-[3-(4-(dimethylamino)benzamido)-propyl]di
N, N '-bis(trifluoroacetyl)- S, S '-bis-L-homocystei
N, N -dimethylanilinium tetrakis(pentafluorophenyl)b
N, N' -ethylenebis(vinylsulfonylacetamide)
N, N,N',N' -tetramethyl-3,3'-(propylenebis(iminocarb
niline
octasodium 2-(6-(4-chloro-6-(3-( N -methyl- N -(4-ch
octasodium 2-(8-(4-chloro-6-(3-((4-chloro-6-(3,6-dis
octhilinone (ISO)
oxiranemethanol, 4-methylbenzene-sulfonate, ( S )-
oxo-((2,2,6,6-tetramethylpiperidin-4-yl)amino)carbon
oxydiethylene bis(chloroformate)
pentasodium 4-amino-6-(5-(4-(2-ethyl-phenylamino)-6-
pentasodium bis{7-[4-(1-butyl-5-cyano-1,2-dihydro-2-
phthalic anhydride
potassium 2,5-dichlorobenzoate
potassium 2-(2,4-dichlorophenoxy)-( R )-propionate
potassium N -(4-fluorophenyl)glycinate
potassium sodium 3,3'-(3(or 4)-methyl-1,2-phenyleneb
potassium sodium 6,13-dichloro-3,10-bis{2-[4-[3-(2-h
product by process iron complex of azo dyestuffs obt
propan-1-ol
propargite (ISO)
reaction mass of 2-acryloyloxyethyl hydrogen cyclohe
reaction mass of 5-chloro-2-methyl-2 H -isothiazol-3
reaction mass of C 12-14 – tert -alkylammonium diphe
reaction mass of isomers of: sodium phenethylnaphtha
reaction mass of: (3-methoxy)propylammonium/[tris-(2
reaction mass of: 2,2'-[[(2-hydroxyethyl)imino]bis(m
reaction mass of: 2,2,6,6-tetramethylpiperidin-4-yl-
reaction mass of: 2-(9-methyl-1,3,8,10-tetraoxo-2,3,
reaction mass of: 2-(hexylthio)ethylamine hydrochlor
reaction mass of: [1-(methoxymethyl)-2-(C 12 -alkoxy
reaction mass of: ammonium-1,2-bis(hexyloxycarbonyl)
reaction mass of: bis(1 S ,2 S ,4 S )-(1-benzyl-4- t
reaction mass of: cis-(5-ammonium-1,3,3-trimethyl)-c
reaction mass of: disodium 6-[3-carboxy-4,5-dihydro-
reaction mass of: dodecanoic acid (35-40 %)
reaction mass of: isobutyl hydrogen 2-(α-2,4,6-trime
reaction mass of: N -aminoethylpiperazonium mono-2,4
reaction mass of: pentasodium 5-amino-3-(5-{4-chloro
reaction mass of: tetradecanoic acid
reaction mass of: tetradecanoic acid (42,5-47,5 %)
reaction mass of: tetrasodium(((2-hydroxyethyl)imino
reaction mass of: thiobis(4,1-phenylene)- S, S,S',S'
reaction mass of: trans -(2 R )-5-acetoxy-1,3-oxathi
reaction mass of: trans -2-(1-methylethyl)-1,3-dioxa
reaction mass of: trihexadecylmethylammonium chlorid
reaction mass of: trilithium 4-amino-3-((4-((4-((2-a
reaction mass of: tris(3,5,5-trimethylhexylammonium)
reaction mass of: trisodium 4-benzoylamino-6-(6-ethe
reaction mass of: trisodium 5{4-chloro-6-[2-(2,6-dic
reaction mass of: trisodium N (1')- N (2): N (1''')-
Reaction product of: 1,2,3-propanetricarboxylic acid
reaction product of: 2-[[4-amino-2-ureidophenylazo]-
salts of 2,4-D
salts of 2,4-DB
salts of aniline
salts of mecoprop
sodium ( R )-2-(2,4-dichlorophenoxy)propionate
sodium (( N -(3-trimethylammoniopropyl)sulfamoyl)met
sodium 2-anilino-5-(2-nitro-4-( N -phenylsulfamoyl))
sodium 2-biphenylate
sodium 3,5-dichloro-2-(5-cyano-2,6-bis(3-hydroxyprop
sodium 3-(2 H -benzotriazol-2- yl)-5- sec -butyl-4-h
sodium hypochlorite, solution … % Cl active
sodium metabisulphite
styrene-4-sulfonyl chloride
subtilisin
succinic anhydride
tetrachlorophthalic anhydride
tetrachloroplatinates with the exception of those sp
tetrahydrothiopyran-3-carboxaldehyde
tetrakis(dimethylditetradecylammonium) hexa-μ-oxotet
tetrakis(trimethylhexadecylammonium) hexa-mu-oxotetr
tetrasodium 4-[4-chloro-6-(4-methyl-2-sulfophenylami
tetrasodium 4-amino-3,6-bis(5-(6-chloro-4-(2-hydroxy
tetrasodium 5-[4-chloro-6-( N -ethyl-anilino)-1,3,5-
tetrasodium dihydrogen 1,1''-dihydroxy-8,8''-[p-phen
trans -4-cyclohexyl-L-proline monohydrochloride
trichlorosilane
triethylamine
trimethylenediaminetetraacetic acid
tris(octadec-9-enylammonium) (trisulfonatophthalocya
trisodium (1-(3-carboxylato-2-oxido-5-sulfonatopheny
trisodium (6-anilino-2-(5-nitro-2-oxidophenylazo)-3-
trisodium 2-{α[2-hydroxy-3-[4-chloro-6-[4-(2,3-dibro
trisodium [2-(5-chloro-2,6-difluoropyrimidin-4-ylami
trisodium bis(2-(5-chloro-4-nitro-2-oxidophenylazo)-
trisodium(2-(α-(3-(4-chloro-6-(2-(2-(vinylsulfonyl)e
vanadium(IV) oxide hydrogen phosphate hemihydrate, l
zinc sulphate (hydrous) (mono-, hexa-and hepta hydra
ziram (ISO)
α, α, α-trichlorotoluene
α, α-dichlorotoluene
α-chlorotoluene

Dove compare H318

Il codice H318 va riportato per esteso sull'etichetta CLP del prodotto, insieme a pittogramma, avvertenza e consigli di prudenza (P), e nella sezione 2 della scheda dati di sicurezza. Per le miscele, la presenza dell'indicazione dipende dalla concentrazione della sostanza e dagli eventuali limiti specifici.

Indicazioni di pericolo correlate

Altri codici H dello stesso tipo di pericolo (salute):

Fonti

Codici delle indicazioni di pericolo secondo gli Allegati III e VI del Regolamento (CE) n. 1272/2008 (CLP). Gli abbinamenti classe–codice derivano dall'Allegato I (elementi dell'etichetta) e dall'Allegato III, parte 1; gli elenchi di sostanze derivano dalla Tabella 3 dell'Allegato VI; il testo ufficiale di H318 è quello dell'Allegato III. Verifica sempre la versione consolidata vigente e l'inventario C&L dell'ECHA.

Domande frequenti

A quale pericolo corrisponde il codice H318?

Nel Regolamento CLP il codice H318 è l'indicazione di pericolo prevista per la classe Gravi lesioni oculari/irritazione oculare, categoria 1 (Eye Dam. 1) (Allegato I; elenco nell'Allegato III, parte 1). Il testo ufficiale per esteso è nell'Allegato III del CLP.

Dove trovo il testo completo di H318?

Nell'Allegato III del CLP: è uguale per tutte le sostanze e va riportato per esteso in etichetta accanto al pittogramma.

Quante sostanze hanno l'indicazione H318?

Nella Tabella 3 dell'Allegato VI il codice H318 compare in numerose voci: in questa pagina ne trovi un elenco collegato alle relative schede.

H318 compare sempre da solo?

No: una sostanza può avere più indicazioni di pericolo. In etichetta vanno riportate tutte quelle pertinenti, con i relativi pittogrammi e consigli di prudenza.

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H318: indicazione di pericolo CLP, classe associata e sostanze