Gravi lesioni oculari (CLP): categorie, pittogramma e sostanze classificate

La classe di pericolo Gravi lesioni oculari (codice Eye Dam., pericolo di tipo salute) è una delle classi previste dal Regolamento CLP (CE) n. 1272/2008. In questa pagina trovi cosa significa, le categorie, il pittogramma e l'avvertenza associati e un elenco di sostanze con questa classificazione armonizzata, ciascuna collegata alla propria scheda.

Che cos'è la classe Eye Dam.

«Gravi lesioni oculari» è la denominazione della classe di pericolo: indica il tipo di pericolo che la sostanza presenta. La gravità è espressa dalla categoria (ad esempio 1, 1A, 1B, 2, 3): più basso è il numero, maggiore è il pericolo. A ogni categoria corrispondono un'indicazione di pericolo (codice H), un pittogramma e un'avvertenza.

Categorie della classe Eye Dam.

Tra le sostanze con classificazione armonizzata in questa classe sono presenti le seguenti categorie:

Pittogramma e avvertenza

Per questa classe, sull'etichetta CLP compaiono tipicamente i seguenti pittogrammi, con l'avvertenza Pericolo:

• GHS05 – Corrosione (corrosivi per pelle/occhi/metalli)
• GHS07 – Punto esclamativo (irritazione, tossicità acuta minore)
• GHS09 – Ambiente (pericoloso per l’ambiente acquatico)

Sostanze classificate come gravi lesioni oculari

Esempi di sostanze con questa classificazione armonizzata (Allegato VI). Apri la scheda per vedere tutti i codici di classe, le indicazioni H e i pittogrammi:

• ( N -benzyl- N -ethyl)amino-3-hydroxyacetophenone hy
• ( S )-α-(acetylthio)benzenepropanoic acid
• ( Z )-1-benzo[ b ]thien-2-ylethanone oxime hydrochlo
• ((4-phenylbutyl)hydroxyphosphoryl)acetic acid
• (-)- trans -4-(4'-fluorophenyl)-3-hydroxymethyl- N –
• (1 R ,4 S )-2-azabicyclo[2.2.1]hept-5-en-3-one
• (2-(1,3-dioxolan-2-yl)ethyl)triphenylphosphonium bro
• (3'-carboxymethyl-5-(2-(3-ethyl-3 H -benzothiazol-2-
• (4-aminophenyl)- N -methylmethylensulfonamide hydroc
• (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-n
• (9 S )-9-amino-9-deoxyerythromycin
• (ethyl-3-oxobutanoato- O '1, O '3)(2-dimethylaminoet
• (±)- trans -4-(4-fluorophenyl)-3-hydroxymethyl- N -m
• (η-cumene)-(η-cyclopentadienyl)iron(II) hexafluoroan
• 1,2,3,6-tetrahydrophthalic anhydride
• 1,2-benzisothiazol-3(2H)-one
• 1,2-dimethylimidazole
• 1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1 H
• 1,3,5-tris-[(2 S and 2 R )-2,3-epoxypropyl]-1,3,5-tr
• 1,3-bis(3-methyl-2,5-dioxo-1 H -pyrrolinylmethyl)ben
• 1,3-bis(vinylsulfonylacetamido)propane
• 1,4,5,8-tetraaminoanthra quinone
• 1,4,7,10-tetraazacyclododecane disulfate
• 1,4-dihydroxybenzene
• 1- tert -butoxypropan-2-ol
• 1-((2-quinolinyl-carbonyl)oxy)-2,5-pyrrolidinedione
• 1-(1-naphthylmethyl)quinolinium chloride
• 1-(2-(ethyl(4-(4-(4-(4-(ethyl(2-pyridinoethyl)amino)
• 1-(3-(4-fluorophenoxy)propyl)3-methoxy-4-piperidinon
• 1-[3-[4-((heptadecafluorononyl)oxy)-benzamido]propyl
• 1-bromo-3,4,5-trifluorobenzene
• 1-chloro- N , N -diethyl-1,1-diphenyl-1-(phenylmethy
• 1-naphtol
• 1-vinyl-2-pyrrolidone
• 2 S -isopropyl-5 R -methyl-1 R -cyclohexyl 2,2-dihyd
• 2,2'-iminodiethanol
• 2,2-bis(hydroxymethyl)butanoic acid
• 2,2-ethylmethylthiazolidine
• 2,3,4-trifluoroaniline
• 2,3,5,6-tetrafluorobenzoic acid
• 2,3,5,6-tetrahydro-2-methyl-2 H -cyclopenta[ d ]-1,2
• 2,3,5-trimethylhydroquinone
• 2,3-dichloro-5-trifluoromethyl- pyridine
• 2,3-dichloropropene
• 2,3-epoxypropyl methacrylate
• 2,4-bis[2,2'-[2-( N, N -dimethylamino)ethyloxycarbon
• 2,4-D (ISO)
• 2,4-dichloro-3-ethyl-6-nitrophenol
• 2,4-difluoro-α-(1 H -1,2,4-triazol-1-yl)acetophenone
• 2,5-dibutoxy-4-(morpholin-4-yl)benzenediazonium 4-me
• 2,6-bis-(2-(4-(4-amino-phenylamino)-phenylazo)-1,3-d
• 2-((4-amino-2-nitrophenyl)amino)benzoic acid
• 2-(2,4-dichlorophenyl)-1-(1 H —1,2,4-triazol-1-yl)pe
• 2-(2-(2-hydroxyethoxy)ethyl)-2-aza-bicyclo[2.2.1]hep
• 2-(2-hexyloxyethoxy)ethanol
• 2-(3-iodoprop-2-yn-1-yloxy)ethyl phenylcarbamate
• 2-(4- tert -butylphenyl)ethanol
• 2-(decylthio)ethylammonium chloride
• 2-(isocyanatosulfonylmethyl)benzoic acid methyl este
• 2-(octylthio)ethanol
• 2-[2-(2-butoxyethoxy)ethoxy]ethanol
• 2-[[4[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-
• 2-alkoyloxyethyl hydrogen maleate, where alkoyl repr
• 2-chloro-4,5-difluorobenzoic acid
• 2-chloromethyl-3,4-dimethoxypyridinium chloride
• 2-hydroxy-3-(2-ethyl-4-methylimidazoyl)propyl neodec
• 2-hydroxy-3-[(2-hydroxyethyl)-[2-(1-oxotetradecyl)am
• 2-hydroxymethyl-9-methyl-6-(1-methylethyl)-1,4-dioxa
• 2-isopropyl-4-( N -methyl)aminomethylthiazole
• 2-methoxypropanol
• 2-methyl-5-(1,1,3,3-tetramethylbutyl)hydroquinone
• 2-methylaziridine
• 2-methylpropan-1-ol
• 2-phenoxyethanol
• 2-{4-(2-ammoniopropylamino)-6-[4-hydroxy-3-(5-methyl
• 3(or 5)-(4-( N -benzyl- N -ethylamino)-2-methylpheny
• 3,4-dichloroaniline
• 3-(2-ethylhexyloxy)propane-1,2-diol
• 3-(3-methylpent-3-yl)isoxazol-5- ylamine
• 3-amino-4-hydroxy- N -(2-methoxyethyl)-benzenesulfon
• 3-aminomethyl-3,5,5-trimethylcyclohexylamine
• 3-azidosulfonylbenzoic acid
• 4,4'-bis(dimethylamino)benzophenone
• 4,4'-ethylidenediphenyl dicyanate
• 4,4'-isopropylidenediphenol
• 4,4'-thiodi- o -cresol
• 4-(1-oxo-2-propenyl)-morpholine
• 4-(2-chloro-4-trifluoromethyl)phenoxy-2-fluoroanilin
• 4-[3-(diethoxymethylsilylpropoxy)-2,2,6,6-tetramethy
• 4-[4-amino-5-hydroxy-3-(4-(2-sulfoxyethylsulfonyl)ph
• 4-cyclohexyl-2-methyl-2-butanol
• 4-dimethylaminobenzenediazonium 3-carboxy-4-hydroxyb
• 4-methyl-N-(methylsulfonyl)benzenesulfonamide
• 4-nitrosophenol
• 5,6-dihydroxyindole
• 5- tert -butyl-3-isoxazolylamine hydrochloride
• 5-acetyl-3-amino-10,11-dihydro-5 H -dibenz[ b, f ]az
• 5-thiazolylmethanol
• 5-{4-[5-amino-2-[4-(2-sulfoxyethylsulfonyl)phenylazo
• 6-(nonylamino)-6-oxo-peroxyhexanoic acid
• 6-(phthalimido)peroxyhexanoic acid
• 6-fluoro-2-methyl-3-(4-methylthiobenzyl)indene
• 6-hydroxyindole
• 8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride
• [ R -( R *, S *)]-[[2-methyl-1-(1-oxopropoxy)propoxy
• A reaction mass of: (1,3-dioxo-2 H -benz(de)isoquino
• acifluorfen (ISO)
• acrylonitrile
• allyl glycidyl ether
• azocyclotin (ISO)
• behenamidopropyl-dimethyl-(dihydroxypropyl) ammonium
• benzene-1,2,4-tricarboxylic acid 1,2-anhydride
• benzene-1,2:4,5-tetracarboxylic dianhydride
• benzyldimethyloctadecylammonium 3-nitrobenzenesulfon
• biphenyl-2-ol
• bis( N -(7-hydroxy-8-methyl-5-phenylphenazin-3-ylide
• bis(3-(trimethoxysilyl)propyl)amine
• bis(dimethyl-(2-hydroxyethyl)ammonium) 1,2-ethanediy
• bis[(1-methylimidazol)-(2-ethyl-hexanoate)], zinc co
• bis[[2,2',2''-nitrilotris-[ethanolato]]-1- N , O ]-b
• bis[tributyl 4-(methylbenzyl)ammonium] 1,5-naphthale
• bronopol (INN)
• butan-1-ol
• butanone oxime
• C 12-14 – tert -alkyl ammonium 1-amino-9,10-dihydro-
• C.I. Basic Violet 3
• C.I. Basic Violet 3 with ≥ 0,1 % of Michler's ketone
• calcium cyanamide
• calcium phosphide
• captan (ISO)
• chlorocresol
• chlorothalonil (ISO)
• cis -1,2,3,6-tetrahydro-4-methylphthalic anhydride
• clopyralid (ISO)
• copper(II) methanesulfonate
• crotonaldehyde
• cyanamide
• cyclohexane-1,2-dicarboxylic anhydride
• cyclopentyl chloroformate
• D, L-( N , N -diethyl-2-hydroxy-2-phenylacetamide)
• dalapon
• di- n -butylamine
• di- tert -(C 12 – 14 )-alkylammonium 2-benzothiazoly
• diamminediisocyanatozinc
• diammonium hexachloroplatinate
• diammonium tetrachloroplatinate
• dibenzylphenylsulfonium hexafluoroantimonate
• dibutyltin hydrogen borate
• dicamba (ISO)
• dichlorprop (ISO)
• dichlorprop-P (ISO)
• dicopper oxide
• dicyclohexylcarbodiimide
• dicyclopentyldimethoxysilane
• dimethyldioctadecylammonium chloride
• dipotassium hexachloroplatinate
• dipotassium tetrachloroplatinate
• disodium (3-methyl-4-(5-nitro-2-oxidophenylazo)-1-ph
• disodium 1-amino-4-(4-benzenesulphonamido-3-sulphona
• disodium 5-[5-[4-(5-chloro-2,6-difluoropyrimidin-4-y
• disodium hexachloroplatinate
• disodium tetrachloroplatinate
• disul (ISO)
• divanadyl pyrophosphate
• DNOC (ISO)
• E -ethyl-4-oxo-4-phenylcrotonate
• ethyl 2-(3-nitrobenzylidene)acetoacetate
• ethyl 2-(isocyanatosulfonyl)benzoate
• ethyl 2-carboxy-3-(2-thienyl)propionate
• ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate
• ethyl lactate
• ethylene oxide
• exo -1-methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]h
• fentin acetate (ISO)
• fentin hydroxide (ISO)
• formic acid … %
• glyphosate (ISO)
• guazatine (ISO)
• hafnium tetra- n -butoxide
• hexachloroplatinates with the exception of those spe
• hexahydro-4-methylphthalic anhydride
• hexasodium (di[ N -(3-(4-[5-(5-amino-3-methyl-1-phen
• hexasodium tungstate hydrate
• hydroxylamine … % [> 55 % in aqueous solution]
• hymexazol (ISO)
• imazalil (ISO)
• lead(II) methanesulphonate
• lithium 1-amino-4-(4-tert-butylanilino)anthraquinone
• lithium sodium (4-((5-chloro-2-hydroxyphenyl)azo)-2,
• magnesium bis(( R )-2-(2,4-dichlorophenoxy)propionat
• main component 6 (isomer): asym. 1:2 Cr(III)-complex
• malachite green hydrochloride
• maleic anhydride
• MCPA (ISO)
• mecoprop (ISO)
• mecoprop-P (ISO) [1] and its salts
• metalaxyl- M (ISO)
• methyl ( R )-2-(4-hydroxyphenoxy)propionate
• methyl 2 R ,3 S -(-)-3-(4-methoxyphenyl)oxiranecarbo
• methyl 4-bromomethyl-3-methoxybenzoate
• methyl chloroacetate
• methyl isocyanate
• methyltriphenylphosphonium chloride
• mono-2-[2-(4-dibenzo[b, f][1,4]thiazepin-11-yl)piper
• mono-methylamine
• mono[2-(dimethylamino)ethyl]monohydrogen-2-(hexadec-
• N , N '-bis{6-chloro-4-[6-(4-vinylsulfonylphenylazo)
• N -[2-hydroxy-3-(C 12-16 -alkyloxy)propyl]- N -methy
• N -cyclohexyl- S, S -dioxo benzo[ b ]tiophene-2-carb
• N -dodecyl-[3-(4-(dimethylamino)benzamido)-propyl]di
• N, N '-bis(trifluoroacetyl)- S, S '-bis-L-homocystei
• N, N -dimethylanilinium tetrakis(pentafluorophenyl)b
• N, N' -ethylenebis(vinylsulfonylacetamide)
• N, N,N',N' -tetramethyl-3,3'-(propylenebis(iminocarb
• niline
• octasodium 2-(6-(4-chloro-6-(3-( N -methyl- N -(4-ch
• octasodium 2-(8-(4-chloro-6-(3-((4-chloro-6-(3,6-dis
• octhilinone (ISO)
• oxiranemethanol, 4-methylbenzene-sulfonate, ( S )-
• oxo-((2,2,6,6-tetramethylpiperidin-4-yl)amino)carbon
• oxydiethylene bis(chloroformate)
• pentasodium 4-amino-6-(5-(4-(2-ethyl-phenylamino)-6-
• pentasodium bis{7-[4-(1-butyl-5-cyano-1,2-dihydro-2-
• phthalic anhydride
• potassium 2,5-dichlorobenzoate
• potassium 2-(2,4-dichlorophenoxy)-( R )-propionate
• potassium N -(4-fluorophenyl)glycinate
• potassium sodium 3,3'-(3(or 4)-methyl-1,2-phenyleneb
• potassium sodium 6,13-dichloro-3,10-bis{2-[4-[3-(2-h
• product by process iron complex of azo dyestuffs obt
• propan-1-ol
• propargite (ISO)
• reaction mass of 2-acryloyloxyethyl hydrogen cyclohe
• reaction mass of 5-chloro-2-methyl-2 H -isothiazol-3
• reaction mass of C 12-14 – tert -alkylammonium diphe
• reaction mass of isomers of: sodium phenethylnaphtha
• reaction mass of: (3-methoxy)propylammonium/[tris-(2
• reaction mass of: 2,2'-[[(2-hydroxyethyl)imino]bis(m
• reaction mass of: 2,2,6,6-tetramethylpiperidin-4-yl-
• reaction mass of: 2-(9-methyl-1,3,8,10-tetraoxo-2,3,
• reaction mass of: 2-(hexylthio)ethylamine hydrochlor
• reaction mass of: [1-(methoxymethyl)-2-(C 12 -alkoxy
• reaction mass of: ammonium-1,2-bis(hexyloxycarbonyl)
• reaction mass of: bis(1 S ,2 S ,4 S )-(1-benzyl-4- t
• reaction mass of: cis-(5-ammonium-1,3,3-trimethyl)-c
• reaction mass of: disodium 6-[3-carboxy-4,5-dihydro-
• reaction mass of: dodecanoic acid (35-40 %)
• reaction mass of: isobutyl hydrogen 2-(α-2,4,6-trime
• reaction mass of: N -aminoethylpiperazonium mono-2,4
• reaction mass of: pentasodium 5-amino-3-(5-{4-chloro
• reaction mass of: tetradecanoic acid
• reaction mass of: tetradecanoic acid (42,5-47,5 %)
• reaction mass of: tetrasodium(((2-hydroxyethyl)imino
• reaction mass of: thiobis(4,1-phenylene)- S, S,S',S'
• reaction mass of: trans -(2 R )-5-acetoxy-1,3-oxathi
• reaction mass of: trans -2-(1-methylethyl)-1,3-dioxa
• reaction mass of: trihexadecylmethylammonium chlorid
• reaction mass of: trilithium 4-amino-3-((4-((4-((2-a
• reaction mass of: tris(3,5,5-trimethylhexylammonium)
• reaction mass of: trisodium 4-benzoylamino-6-(6-ethe
• reaction mass of: trisodium 5{4-chloro-6-[2-(2,6-dic
• reaction mass of: trisodium N (1')- N (2): N (1''')-
• Reaction product of: 1,2,3-propanetricarboxylic acid
• reaction product of: 2-[[4-amino-2-ureidophenylazo]-
• salts of 2,4-D
• salts of 2,4-DB
• salts of aniline
• salts of mecoprop
• sodium ( R )-2-(2,4-dichlorophenoxy)propionate
• sodium (( N -(3-trimethylammoniopropyl)sulfamoyl)met
• sodium 2-anilino-5-(2-nitro-4-( N -phenylsulfamoyl))
• sodium 2-biphenylate
• sodium 3,5-dichloro-2-(5-cyano-2,6-bis(3-hydroxyprop
• sodium 3-(2 H -benzotriazol-2- yl)-5- sec -butyl-4-h
• sodium hypochlorite, solution … % Cl active
• sodium metabisulphite
• styrene-4-sulfonyl chloride
• subtilisin
• succinic anhydride
• tetrachlorophthalic anhydride
• tetrachloroplatinates with the exception of those sp
• tetrahydrothiopyran-3-carboxaldehyde
• tetrakis(dimethylditetradecylammonium) hexa-μ-oxotet
• tetrakis(trimethylhexadecylammonium) hexa-mu-oxotetr
• tetrasodium 4-[4-chloro-6-(4-methyl-2-sulfophenylami
• tetrasodium 4-amino-3,6-bis(5-(6-chloro-4-(2-hydroxy
• tetrasodium 5-[4-chloro-6-( N -ethyl-anilino)-1,3,5-
• tetrasodium dihydrogen 1,1''-dihydroxy-8,8''-[p-phen
• trans -4-cyclohexyl-L-proline monohydrochloride
• trichlorosilane
• triethylamine
• trimethylenediaminetetraacetic acid
• tris(octadec-9-enylammonium) (trisulfonatophthalocya
• trisodium (1-(3-carboxylato-2-oxido-5-sulfonatopheny
• trisodium (6-anilino-2-(5-nitro-2-oxidophenylazo)-3-
• trisodium 2-{α[2-hydroxy-3-[4-chloro-6-[4-(2,3-dibro
• trisodium [2-(5-chloro-2,6-difluoropyrimidin-4-ylami
• trisodium bis(2-(5-chloro-4-nitro-2-oxidophenylazo)-
• trisodium(2-(α-(3-(4-chloro-6-(2-(2-(vinylsulfonyl)e
• vanadium(IV) oxide hydrogen phosphate hemihydrate, l
• zinc sulphate (hydrous) (mono-, hexa-and hepta hydra
• ziram (ISO)
• α, α, α-trichlorotoluene
• α, α-dichlorotoluene
• α-chlorotoluene

Obblighi pratici

Se un prodotto contiene una sostanza di questa classe sopra le soglie pertinenti, la classificazione si riflette su etichetta CLP (pittogramma, avvertenza, indicazioni H, consigli P), scheda dati di sicurezza (sezioni 2 e 15), imballaggio ed eventuale notifica al centro antiveleni. Per le miscele il contributo dipende dalla concentrazione e da eventuali limiti specifici o fattori M.

Altre classi di pericolo salute

Il CLP raggruppa le classi in pericoli fisici, per la salute e per l'ambiente. Altre classi del gruppo «salute»:

• Tossicità acuta (Acute Tox.)
• Corrosione della pelle (Skin Corr.)
• Irritazione cutanea (Skin Irrit.)
• Irritazione oculare (Eye Irrit.)
• Sensibilizzazione respiratoria (Resp. Sens.)
• Sensibilizzazione cutanea (Skin Sens.)
• Mutagenicità sulle cellule germinali (Muta.)
• Cancerogenicità (Carc.)
• Tossicità per la riproduzione (Repr.)
• Effetti sull’allattamento o attraverso l’allattamento (Lact.)
• Tossicità specifica per organi bersaglio – esposizione singola (STOT SE)
• Tossicità specifica per organi bersaglio – esposizione ripetuta (STOT RE)
• Pericolo in caso di aspirazione (Asp. Tox.)

Fonti

Classe e categorie secondo l'Allegato I e l'Allegato VI del Regolamento (CE) n. 1272/2008 (CLP). Gli elenchi di sostanze derivano dalla Tabella 3.1 dell'Allegato VI; verifica sempre la versione consolidata vigente e l'inventario C&L dell'ECHA.

Domande frequenti

Come faccio a sapere se una sostanza rientra in questa classe?

Si controlla la sua classificazione: nelle schede per sostanza trovi i codici di classe e categoria di pericolo tratti dall'Allegato VI del CLP, oppure si applica l'autoclassificazione sulla base dei dati disponibili.

Questa classe richiede un pittogramma in etichetta?

Sì, quando previsto dalla categoria: in etichetta CLP vanno riportati pittogramma, avvertenza, indicazioni di pericolo (H) e consigli di prudenza (P) coerenti con la classificazione.

Dove ritrovo l'elenco completo delle sostanze gravi lesioni oculari?

In questa pagina trovi gli esempi collegati alle schede; l'elenco completo è nell'archivio delle schede CLP per sostanza.

La classificazione può cambiare nel tempo?

Sì: gli ATP (adeguamenti al progresso tecnico) aggiornano l'Allegato VI. Verifica sempre la versione consolidata vigente e l'inventario C&L dell'ECHA.