Mutagenicità sulle cellule germinali (CLP): categorie, pittogramma e sostanze classificate

La classe di pericolo Mutagenicità sulle cellule germinali (codice Muta., pericolo di tipo salute) è una delle classi previste dal Regolamento CLP (CE) n. 1272/2008. In questa pagina trovi cosa significa, le categorie, il pittogramma e l'avvertenza associati e un elenco di sostanze con questa classificazione armonizzata, ciascuna collegata alla propria scheda.

Che cos'è la classe Muta.

«Mutagenicità sulle cellule germinali» è la denominazione della classe di pericolo: indica il tipo di pericolo che la sostanza presenta. La gravità è espressa dalla categoria (ad esempio 1, 1A, 1B, 2, 3): più basso è il numero, maggiore è il pericolo. A ogni categoria corrispondono un'indicazione di pericolo (codice H), un pittogramma e un'avvertenza.

Categorie della classe Muta.

Tra le sostanze con classificazione armonizzata in questa classe sono presenti le seguenti categorie:

Pittogramma e avvertenza

Per questa classe, sull'etichetta CLP compaiono tipicamente i seguenti pittogrammi, con l'avvertenza Pericolo:

• GHS08 – Pericolo per la salute (CMR, sensibilizzanti respiratori, aspirazione, STOT)
• GHS02 – Fiamma (infiammabili)
• GHS04 – Bombola per gas (gas sotto pressione)

Sostanze classificate come mutagenicità sulle cellule germinali

Esempi di sostanze con questa classificazione armonizzata (Allegato VI). Apri la scheda per vedere tutti i codici di classe, le indicazioni H e i pittogrammi:

• (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone
• (4-hydrazinophenyl)- N -methylmethanesulfonamide hyd
• 1,2-dibromo-3-chloropropane
• 1,2-dihydroxybenzene
• 1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1 H
• 1,3,5-tris-[(2 S and 2 R )-2,3-epoxypropyl]-1,3,5-tr
• 1,3-bis(vinylsulfonylacetamido)propane
• 1,3-butadiene
• 1,4-dihydroxybenzene
• 1-(1-naphthylmethyl)quinolinium chloride
• 1-chloro-4-nitrobenzene
• 2,2'-bioxirane
• 2,3-dichloropropene
• 2,3-dinitrotoluene
• 2,3-epoxypropan-1-ol
• 2,3-epoxypropyl methacrylate
• 2,4-diaminoanisole
• 2,4-dinitrotoluene
• 2,5-dinitrotoluene
• 2,6-dinitrotoluene
• 2-(isocyanatosulfonylmethyl)benzoic acid methyl este
• 2-aminophenol
• 2-methoxyaniline
• 2-methyl- m -phenylenediamine
• 2-nitrotoluene
• 3,4-dinitrotoluene
• 3,5-dinitrotoluene
• 3-chloropropene
• 4'-ethoxy-2-benzimidazoleanilide
• 4,4'-bis(dimethylamino)benzophenone
• 4,4'-diaminodiphenylmethane
• 4,4'-oxydianiline and its salts
• 4-aminophenol
• 4-chloro-o-toluidine
• 4-ethoxyaniline
• 4-methyl- m -phenylenediamine
• 4-nitrosophenol
• 7-oxa-3-oxiranylbicyclo[4.1.0]heptane
• 9-vinylcarbazole
• [( p -tolyloxy)methyl]oxirane
• acetaldehyde
• acrylamide
• Alkanes, C 1-2
• Alkanes, C 1-4 , C 3 -rich
• Alkanes, C 2-3
• Alkanes, C 3-4
• Alkanes, C 4-5
• allyl glycidyl ether
• ammonium dichromate
• Aromatic hydrocarbons, C 6-10 , acid-treated, neutra
• Aromatic hydrocarbons, C 6-8 , naphtha-raffinate pyr
• Aromatic hydrocarbons, C 7-12 , C 8 -rich
• Aromatic hydrocarbons, C 7-8 , dealkylation products
• Aromatic hydrocarbons, C 8 , catalytic reforming-der
• Aromatic hydrocarbons, C 8-10
• azobenzene
• benomyl (ISO)
• benzene
• benzo[ a ]pyrene
• bromomethane
• butane (containing ≥ 0,1 % butadiene (203-450-8))
• butyl glycidyl ether
• C.I. Solvent Yellow 14
• cadmium (non-pyrophoric)
• cadmium (pyrophoric)
• cadmium chloride
• cadmium fluoride
• cadmium sulphate
• cadmium sulphide
• carbendazim (ISO)
• chromium (VI) trioxide
• chromyl dichloride
• chrysene
• cobalt
• cobalt dichloride
• cobalt sulfate
• crotonaldehyde
• cycloheximide (ISO)
• di- tert -butyl peroxide
• dibutyltin hydrogen borate
• diethyl sulphate
• dimethyl sulphate
• Distillates (petroleum), C 3-5 , 2-methyl-2-butene-r
• Distillates (petroleum), C 3-6 , piperylene-rich
• Distillates (petroleum), C 6 -rich
• Distillates (petroleum), C 7-9 , C 8 -rich, hydrodes
• Distillates (petroleum), catalytic reformed depentan
• Distillates (petroleum), catalytic reformed hydrotre
• Distillates (petroleum), catalytic reformed straight
• Distillates (petroleum), depentanizer overheads
• Distillates (petroleum), heat-soaked steam-cracked n
• Distillates (petroleum), heavy arom.
• Distillates (petroleum), hydrotreated heavy naphtha,
• Distillates (petroleum), hydrotreated middle, interm
• Distillates (petroleum), light arom.
• Distillates (petroleum), light distillate hydrotreat
• Distillates (petroleum), light straight-run gasoline
• Distillates (petroleum), light thermal cracked, debu
• Distillates (petroleum), naphtha steam cracking-deri
• Distillates (petroleum), naphtha steam cracking-deri
• Distillates (petroleum), naphtha unifiner stripper
• Distillates (petroleum), naphtha-raffinate pyrolyzat
• Distillates (petroleum), polymd. steam-cracked petro
• Distillates (petroleum), steam-cracked, C 5-10 fract
• Distillates (petroleum), steam-cracked, C 5-12 fract
• Distillates (petroleum), steam-cracked, C 8-12 fract
• Distillates (petroleum), straight-run light
• Distillates (petroleum), thermal cracked naphtha and
• Distillates (petroleum), thermal cracked naphtha and
• Distillates (petroleum), thermal cracked naphtha and
• divanadium pentaoxide
• DNOC (ISO)
• ethylene oxide
• ethyleneimine
• Extracts (petroleum) heavy naphtha solvent, clay-tre
• Extracts (petroleum), catalytic reformed light napht
• Extracts (petroleum), cold-acid, C 4-6
• fenthion (ISO)
• formaldehyde … %
• Fuel gases
• Fuel gases, crude oil of distillates
• furan
• Gases (petroleum), alkylation feed
• Gases (petroleum), amine system feed
• Gases (petroleum), benzene unit hydrodesulfurizer of
• Gases (petroleum), benzene unit hydrotreater depenta
• Gases (petroleum), benzene unit recycle, hydrogen-ri
• Gases (petroleum), blend oil, hydrogen-nitrogen-rich
• Gases (petroleum), butane splitter overheads
• Gases (petroleum), C 1-5 , wet
• Gases (petroleum), C 2 -return stream
• Gases (petroleum), C 2-3 –
• Gases (petroleum), C 2-4 , sweetened
• Gases (petroleum), C 3-4
• Gases (petroleum), C 3-4 , isobutane-rich
• Gases (petroleum), C 3-5 olefinic-paraffinic alkylat
• Gases (petroleum), C 4 -rich
• Gases (petroleum), C 6-8 catalytic reformer
• Gases (petroleum), C 6-8 catalytic reformer recycle
• Gases (petroleum), C 6-8 catalytic reformer recycle,
• Gases (petroleum), catalytic cracked naphtha debutan
• Gases (petroleum), catalytic cracked naphtha depropa
• Gases (petroleum), catalytic cracked overheads
• Gases (petroleum), catalytic cracker
• Gases (petroleum), catalytic cracker, C 1-5 -rich
• Gases (petroleum), catalytic cracking
• Gases (petroleum), catalytic polymd. naphtha stabili
• Gases (petroleum), catalytic reformed naphtha stripp
• Gases (petroleum), catalytic reformed straight-run n
• Gases (petroleum), catalytic reformer, C 1-4 -rich
• Gases (petroleum), catalytic-cracked gas oil depropa
• Gases (petroleum), catalytic-cracked naphtha debutan
• Gases (petroleum), crude distn. and catalytic cracki
• Gases (petroleum), crude oil fractionation off
• Gases (petroleum), deethanizer overheads
• Gases (petroleum), dehexanizer off
• Gases (petroleum), depropanizer bottoms fractionatio
• Gases (petroleum), depropanizer dry, propene-rich
• Gases (petroleum), depropanizer overheads
• Gases (petroleum), distillate unifiner desulfurizati
• Gases (petroleum), dry sour, gas-concn.-unit-off
• Gases (petroleum), fluidized catalytic cracker fract
• Gases (petroleum), fluidized catalytic cracker scrub
• Gases (petroleum), full-range straight-run naphtha d
• Gases (petroleum), gas concn. reabsorber distn.
• Gases (petroleum), gas oil diethanolamine scrubber o
• Gases (petroleum), gas oil hydrodesulfurization effl
• Gases (petroleum), gas oil hydrodesulfurization purg
• Gases (petroleum), gas recovery plant depropanizer o
• Gases (petroleum), Girbotol unit feed
• Gases (petroleum), heavy distillate hydrotreater des
• Gases (petroleum), hydrocracking depropanizer off, h
• Gases (petroleum), hydrocracking low-pressure separa
• Gases (petroleum), hydrogen absorber off
• Gases (petroleum), hydrogen-rich
• Gases (petroleum), hydrogenator effluent flash drum
• Gases (petroleum), hydrotreated sour kerosine depent
• Gases (petroleum), hydrotreated sour kerosine flash
• Gases (petroleum), hydrotreater blend oil recycle, h
• Gases (petroleum), isomerized naphtha fractionator,
• Gases (petroleum), light straight run gasoline fract
• Gases (petroleum), light straight-run naphtha stabil
• Gases (petroleum), naphtha steam cracking high-press
• Gases (petroleum), naphtha unifiner desulfurization
• Gases (petroleum), oil refinery gas distn. off
• Gases (petroleum), platformer products separator off
• Gases (petroleum), platformer stabilizer off, light
• Gases (petroleum), preflash tower off, crude distn.
• Gases (petroleum), recycle, hydrogen-rich
• Gases (petroleum), refinery
• Gases (petroleum), refinery blend
• Gases (petroleum), reformer effluent high-pressure f
• Gases (petroleum), reformer effluent low-pressure fl
• Gases (petroleum), reformer make-up, hydrogen-rich
• Gases (petroleum), reforming hydrotreater
• Gases (petroleum), reforming hydrotreater make-up, h
• Gases (petroleum), reforming hydrotreater, hydrogen-
• Gases (petroleum), residue visbaking off
• Gases (petroleum), secondary absorber off, fluidized
• Gases (petroleum), sponge absorber off, fluidized ca
• Gases (petroleum), steam-cracker C 3 -rich
• Gases (petroleum), straight-run naphtha catalytic re
• Gases (petroleum), straight-run naphtha catalytic re
• Gases (petroleum), straight-run stabilizer off
• Gases (petroleum), tar stripper off
• Gases (petroleum), thermal cracking distn.
• Gases (petroleum), unifiner stripper off
• Gases (petroleum, light steam-cracked, butadiene con
• Gases(petroleum), fluidized catalytic cracker splitt
• Gasespetroleum),deisobutanizer tower overheads
• Gasoline
• Gasoline, C 5-11 , high-octane stabilised reformed
• Gasoline, natural
• Gasoline, pyrolysis, debutanizer bottoms
• Gasoline, pyrolysis, hydrogenated
• Gasoline, straight-run, topping-plant
• Gasoline, vapor-recovery
• glyoxal…%
• hexahydrocyclopenta[ c ]pyrrole-1-(1 H )-ammonium N
• hexamethylphosphoric triamide
• Hydrocarbons, C 1-3
• Hydrocarbons, C 1-4
• Hydrocarbons, C 1-4 , debutanizer fraction
• Hydrocarbons, C 1-4 , sweetened
• Hydrocarbons, C 2-4
• Hydrocarbons, C 2-4 , C 3 -rich
• Hydrocarbons, C 2-6 , C 6-8 catalytic reformer
• Hydrocarbons, C 3
• Hydrocarbons, C 3-11 , catalytic cracker distillates
• Hydrocarbons, C 3-4
• Hydrocarbons, C 3-4 -rich, petroleum distillate
• Hydrocarbons, C 3-6 , C 5 -rich, steam-cracked napht
• Hydrocarbons, C 4
• Hydrocarbons, C 4 , 1,3-butadiene-and isobutene-free
• Hydrocarbons, C 4 , steam-cracker distillate
• Hydrocarbons, C 4-11 , naphtha-cracking, arom.-free
• Hydrocarbons, C 4-12 , naphtha-cracking, hydrotreate
• Hydrocarbons, C 4-5
• Hydrocarbons, C 4-6 , depentanizer lights, arom. hyd
• Hydrocarbons, C 5 -rich
• Hydrocarbons, C 5 -rich, dicyclopentadiene-contg.
• Hydrocarbons, C 5-11 , nonaroms.-rich, reforming lig
• Hydrocarbons, C 6 -rich, hydrotreated light naphtha
• Hydrocarbons, C 6-11 , hydrotreated, dearomatized
• Hydrocarbons, C 6-8 , hydrogenated sorption-dearomat
• Hydrocarbons, C 7-12 , C≥9-arom.-rich, reforming hea
• Hydrocarbons, C 8-11 , naphtha-cracking, toluene cut
• Hydrocarbons, C 8-12 , catalytic cracker distillates
• Hydrocarbons, C 8-12 , catalytic cracking, chem. neu
• Hydrocarbons, C 8-12 , catalytic-cracking, chem. neu
• Hydrocarbons, C 9-12 , hydrotreated, dearomatized
• Hydrocarbons, C≥5, C 5-6 -rich
• Hydrocarbons, hydrotreated light naphtha distillates
• isobutyl nitrite
• isoprene (stabilised) 2-methyl-1,3-butadiene
• Ligroine
• m -bis(2,3-epoxypropoxy)benzene
• m -phenylenediamine
• m -phenylenediamine dihydrochloride
• mercury dichloride
• methyl acrylamidoglycolate (containing ≥ 0,1 % acryl
• methyl acrylamidomethoxyacetate (containing ≥ 0,1 %
• methyl-phenylene diamine
• monocrotophos (ISO)
• N , N , N ', N '-tetraglycidyl-4,4'-diamino-3,3'-die
• Naphtha
• Naphtha (petroleum) sweetened
• Naphtha (petroleum), arom.-contg.
• Naphtha (petroleum), catalytic cracked light distd.
• Naphtha (petroleum), catalytic dewaxed
• Naphtha (petroleum), catalytic reformed
• Naphtha (petroleum), catalytic reformed light, arom.
• Naphtha (petroleum), chemically neutralized heavy
• Naphtha (petroleum), chemically neutralized light
• Naphtha (petroleum), clay-treated full-range straigh
• Naphtha (petroleum), clay-treated light straight-run
• Naphtha (petroleum), full-range alkylate
• Naphtha (petroleum), full-range coker
• Naphtha (petroleum), full-range reformed
• Naphtha (petroleum), full-range straight-run
• Naphtha (petroleum), heavy alkylate
• Naphtha (petroleum), heavy catalytic cracked
• Naphtha (petroleum), heavy catalytic cracked, sweete
• Naphtha (petroleum), heavy catalytic reformed
• Naphtha (petroleum), heavy hydrocracked
• Naphtha (petroleum), heavy straight run, arom.-contg
• Naphtha (petroleum), heavy straight-run
• Naphtha (petroleum), heavy thermal cracked
• Naphtha (petroleum), hydrodesulfurised full-range co
• Naphtha (petroleum), hydrodesulfurized full-range
• Naphtha (petroleum), hydrodesulfurized light
• Naphtha (petroleum), hydrodesulfurized light, dearom
• Naphtha (petroleum), hydrodesulfurized thermal crack
• naphtha (petroleum), hydrodesulphurized heavy
• Naphtha (petroleum), hydrotreated heavy
• Naphtha (petroleum), hydrotreated light
• Naphtha (petroleum), hydrotreated light steam-cracke
• Naphtha (petroleum), hydrotreated light, cycloalkane
• Naphtha (petroleum), isomerisation, C 6 -fraction
• Naphtha (petroleum), isomerization
• Naphtha (petroleum), light alkylate
• Naphtha (petroleum), light catalytic cracked
• Naphtha (petroleum), light catalytic cracked sweeten
• Naphtha (petroleum), light catalytic reformed
• Naphtha (petroleum), light catalytic reformed, arom.
• Naphtha (petroleum), light heat-soaked, steam-cracke
• Naphtha (petroleum), light hydrocracked
• Naphtha (petroleum), light steam-cracked
• Naphtha (petroleum), light steam-cracked arom.
• Naphtha (petroleum), light steam-cracked, debenzeniz
• Naphtha (petroleum), light steam-cracked, hydrogenat
• Naphtha (petroleum), light steam-cracked, thermally
• Naphtha (petroleum), light straight-run
• Naphtha (petroleum), light thermal cracked
• Naphtha (petroleum), light thermal cracked, sweetene
• Naphtha (petroleum), light, C 5 -rich, sweetened
• Naphtha (petroleum), light, sweetened
• Naphtha (petroleum), solvent-refined heavy
• Naphtha (petroleum), solvent-refined light
• Naphtha (petroleum), steam-cracked middle arom.
• Naphtha (petroleum), sweetened light
• Naphtha (petroleum), unsweetened
• Naphtha (petroleum),C 4-12 , butane-alkylate, isooct
• Naphtha (petroleum),heavy steam-cracked, hydrogenate
• Naphtha (petroleum),light steam-cracked, debenzenize
• Naphtha(petroleum), acid-treated
• Natural gas (petroleum), raw liq. mix
• Natural gas condensates
• Natural gas condensates (petroleum)
• nickel (II) sulfide
• nickel carbonate
• nickel dihydroxide
• nickel sulfate
• niline
• o -phenylenediamine
• o -phenylenediamine dihydrochloride
• oxiranemethanol, 4-methylbenzene-sulfonate, ( S )-
• Petroleum gases, liquefied
• Petroleum gases, liquefied, sweetened
• Petroleum gases, liquefied, sweetened, C 4 fraction
• Petroleum products, hydrofiner-powerformer reformate
• Petroleum products, refinery gases
• phenol
• phenyl glycidyl ether
• phenylhydrazine
• phosphamidon (ISO)
• potassium chromate
• potassium dichromate
• propylene oxide
• pyrogallol
• R —2,3-epoxy-1-propanol
• Raffinates (petroleum), catalytic reformer ethylene
• Raffinates (petroleum), reformer, Lurgi unit-sepd.
• Raffinates (petroleum), steam-cracked C 4 fraction c
• reaction mass of: 4-allyl-2,6-bis(2,3-epoxypropyl)ph
• reaction mass of: N -[3-hydroxy-2-(2-methylacryloyla
• Residual oils (petroleum), deisobutanizer tower
• Residues (petroleum), alkylation splitter, C 4 -rich
• Residues (petroleum), butane splitter bottoms
• Residues (petroleum), C 6-8 catalytic reformer
• Residues (petroleum), steam-cracked light, arom.
• safrole
• salts of aniline
• sodium chromate
• sodium dichromate
• Solvent naphtha (petroleum), hydrotreated light naph
• Solvent naphtha (petroleum), light aliph.
• Solvent naphtha (petroleum), light arom.
• Solvent naphtha (petroleum), light arom., hydrotreat
• stoddard solvent
• Tail gas (petroleum), catalytic cracked clarified oi
• Tail gas (petroleum), catalytic cracked distillate a
• Tail gas (petroleum), catalytic cracked distillate a
• Tail gas (petroleum), catalytic cracked naphtha stab
• Tail gas (petroleum), catalytic cracker refractionat
• Tail gas (petroleum), catalytic cracker, catalytic r
• Tail gas (petroleum), catalytic hydrodesulfurized na
• Tail gas (petroleum), catalytic polymn. naphtha frac
• Tail gas (petroleum), catalytic reformed naphtha fra
• Tail gas (petroleum), catalytic reformed naphtha fra
• Tail gas (petroleum), catalytic reformed naphtha sep
• Tail gas (petroleum), catalytic reformed naphtha sta
• Tail gas (petroleum), cracked distillate hydrotreate
• Tail gas (petroleum), cracked distillate hydrotreate
• Tail gas (petroleum), gas oil catalytic cracking abs
• Tail gas (petroleum), gas recovery plant
• Tail gas (petroleum), gas recovery plant deethanizer
• Tail gas (petroleum), hydrodesulfurized distillate a
• Tail gas (petroleum), hydrodesulfurized straight-run
• Tail gas (petroleum), hydrodesulfurized vacuum gas o
• Tail gas (petroleum), isomerized naphtha fractionati
• Tail gas (petroleum), light straight-run naphtha sta
• Tail gas (petroleum), propane-propylene alkylation f
• Tail gas (petroleum), saturate gas plant mixed strea
• Tail gas (petroleum), saturate gas recovery plant, C
• Tail gas (petroleum), straight-run distillate hydrod
• Tail gas (petroleum), straight-run naphtha hydrodesu
• Tail gas (petroleum), thermal cracked hydrocarbon fr
• Tail gas (petroleum), thermal-cracked distillate, ga
• Tail gas (petroleum), vacuum gas oil hydrodesulfuriz
• Tail gas (petroleum), vacuum residues thermal cracke
• thiophanate-methyl (ISO)
• trichloroethylene
• trinickel disulfide

Obblighi pratici

Se un prodotto contiene una sostanza di questa classe sopra le soglie pertinenti, la classificazione si riflette su etichetta CLP (pittogramma, avvertenza, indicazioni H, consigli P), scheda dati di sicurezza (sezioni 2 e 15), imballaggio ed eventuale notifica al centro antiveleni. Per le miscele il contributo dipende dalla concentrazione e da eventuali limiti specifici o fattori M.

Altre classi di pericolo salute

Il CLP raggruppa le classi in pericoli fisici, per la salute e per l'ambiente. Altre classi del gruppo «salute»:

• Tossicità acuta (Acute Tox.)
• Corrosione della pelle (Skin Corr.)
• Irritazione cutanea (Skin Irrit.)
• Gravi lesioni oculari (Eye Dam.)
• Irritazione oculare (Eye Irrit.)
• Sensibilizzazione respiratoria (Resp. Sens.)
• Sensibilizzazione cutanea (Skin Sens.)
• Cancerogenicità (Carc.)
• Tossicità per la riproduzione (Repr.)
• Effetti sull’allattamento o attraverso l’allattamento (Lact.)
• Tossicità specifica per organi bersaglio – esposizione singola (STOT SE)
• Tossicità specifica per organi bersaglio – esposizione ripetuta (STOT RE)
• Pericolo in caso di aspirazione (Asp. Tox.)

Fonti

Classe e categorie secondo l'Allegato I e l'Allegato VI del Regolamento (CE) n. 1272/2008 (CLP). Gli elenchi di sostanze derivano dalla Tabella 3.1 dell'Allegato VI; verifica sempre la versione consolidata vigente e l'inventario C&L dell'ECHA.

Domande frequenti

Come faccio a sapere se una sostanza rientra in questa classe?

Si controlla la sua classificazione: nelle schede per sostanza trovi i codici di classe e categoria di pericolo tratti dall'Allegato VI del CLP, oppure si applica l'autoclassificazione sulla base dei dati disponibili.

Questa classe richiede un pittogramma in etichetta?

Sì, quando previsto dalla categoria: in etichetta CLP vanno riportati pittogramma, avvertenza, indicazioni di pericolo (H) e consigli di prudenza (P) coerenti con la classificazione.

Dove ritrovo l'elenco completo delle sostanze mutagenicità sulle cellule germinali?

In questa pagina trovi gli esempi collegati alle schede; l'elenco completo è nell'archivio delle schede CLP per sostanza.

La classificazione può cambiare nel tempo?

Sì: gli ATP (adeguamenti al progresso tecnico) aggiornano l'Allegato VI. Verifica sempre la versione consolidata vigente e l'inventario C&L dell'ECHA.