Irritazione cutanea (CLP): categorie, pittogramma e sostanze classificate

La classe di pericolo Irritazione cutanea (codice Skin Irrit., pericolo di tipo salute) è una delle classi previste dal Regolamento CLP (CE) n. 1272/2008. In questa pagina trovi cosa significa, le categorie, il pittogramma e l'avvertenza associati e un elenco di sostanze con questa classificazione armonizzata, ciascuna collegata alla propria scheda.

Che cos'è la classe Skin Irrit.

«Irritazione cutanea» è la denominazione della classe di pericolo: indica il tipo di pericolo che la sostanza presenta. La gravità è espressa dalla categoria (ad esempio 1, 1A, 1B, 2, 3): più basso è il numero, maggiore è il pericolo. A ogni categoria corrispondono un'indicazione di pericolo (codice H), un pittogramma e un'avvertenza.

Categorie della classe Skin Irrit.

Tra le sostanze con classificazione armonizzata in questa classe sono presenti le seguenti categorie:

Pittogramma e avvertenza

Per questa classe, sull'etichetta CLP compaiono tipicamente i seguenti pittogrammi, con l'avvertenza Pericolo:

• GHS07 – Punto esclamativo (irritazione, tossicità acuta minore)
• GHS09 – Ambiente (pericoloso per l’ambiente acquatico)
• GHS08 – Pericolo per la salute (CMR, sensibilizzanti respiratori, aspirazione, STOT)

Sostanze classificate come irritazione cutanea

Esempi di sostanze con questa classificazione armonizzata (Allegato VI). Apri la scheda per vedere tutti i codici di classe, le indicazioni H e i pittogrammi:

• ( E )-3,7-dimethyl-2,6-octadienylhexadecanoate
• (1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanedi
• (2 R ,6a S ,12a S )-1,2,6,6a,12,12a-hexahydro-2-isop
• (benzothiazol-2-ylthio)methyl thiocyanate
• (C 16 or C 18 -n-alkyl)(C 16 or C 18 -n-alkyl)ammoni
• (±) trans —3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent
• 1,1-diethoxyethane
• 1,1-dimethyl-3-phenyluronium trichloroacetate
• 1,2,3,4-tetrahydronaphthalene
• 1,2,4-trichlorobenzene
• 1,2,4-trimethylbenzene
• 1,2-benzisothiazol-3(2H)-one
• 1,2-dibromoethane
• 1,2-dichlorobenzene
• 1,2-dichloroethane
• 1,2-dihydroxybenzene
• 1,2-dimethylimidazole
• 1,2-epoxybutane
• 1,3-bis(2,3-epoxypropoxy)-2,2-dimethylpropane
• 1,3-dichloro-4-fluorobenzene
• 1,3-dichloropropene
• 1,3-dimethyl-1,3-bis(trimethylsilyl)urea
• 1,3-diphenylguanidine
• 1,4,5,6,7,7-hexachlorobicyclo [2,2,1]hept-5-ene-2,3-
• 1,4,5,8-tetraaminoanthra quinone
• 1,4-bis(2,3 epoxypropoxy)butane
• 1,4-dimethylcyclohexane
• 1-(1-naphthylmethyl)quinolinium chloride
• 1-allyl-3-chloro-4-fluorobenzene
• 1-bromo-3,4,5-trifluorobenzene
• 1-bromo-3,5-difluorobenzene
• 1-bromopropane
• 1-methyl-3-nitro-1-nitrosoguanidine
• 1-naphtol
• 2,2'-(ethylenedioxy)diethyl diacrylate
• 2,2'-iminodiethanol
• 2,2'-oxydiethyl diacrylate
• 2,2,4-trimethylhexamethylene-1,6-di-isocyanate
• 2,2-dimethyl 3-methyl-3-butenyl propanoate
• 2,2-dimethyltrimethylene diacrylate
• 2,3,4,6-tetrachlorophenol
• 2,3,4-trichlorobut-1-ene
• 2,3,4-trifluoroaniline
• 2,3,5,6-tetrafluorobenzoic acid
• 2,3,5-trimethylhydroquinone
• 2,3-dichloropropene
• 2,3-epoxypropan-1-ol
• 2,3-epoxypropyl-2-ethylcyclohexyl ether
• 2,4,4,7-tetramethyl-6-octen-3-one
• 2,4,5-T (ISO)
• 2,4,5-trichlorophenol
• 2,4,6-trichlorophenol
• 2,4,6-tris(dimethylaminomethyl)phenol
• 2,4-di- tert -butylcyclohexanone
• 2,4-dimethyl-6-(1-methyl-pentadecyl)phenol
• 2,5,7,7-tetramethyloctanal
• 2,6-dichloro-4-trifluoromethylaniline
• 2,6-xylidine
• 2- n -hexadecylhydroquinone
• 2- tert -butylaminoethyl methacrylate
• 2-(2,4-dichlorophenyl)-2-(2-propenyl)oxirane
• 2-(2-(2-hydroxyethoxy)ethyl)-2-aza-bicyclo[2.2.1]hep
• 2-(3,4-dichlorophenyl)-4-methyl-1,2,4-oxadiazolidine
• 2-(4-(4-cyano-3-methylisothiazol-5-ylazo)- N -ethyl-
• 2-(decylthio)ethylammonium chloride
• 2-(morpholinothio)benzothiazole
• 2-alkoyloxyethyl hydrogen maleate, where alkoyl repr
• 2-amino-2-methylpropanol
• 2-aminopropane
• 2-butoxyethanol
• 2-chloro-5- sec -hexadecylhydroquinone
• 2-chloro-5-methyl-pyridine
• 2-chloromethyl-3,4-dimethoxypyridinium chloride
• 2-diethylaminoethyl methacrylate
• 2-dimethylaminoethyl methacrylate
• 2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl
• 2-ethylhexyl acrylate
• 2-furaldehyde
• 2-hydroxy-3-(2-ethyl-4-methylimidazoyl)propyl neodec
• 2-hydroxyethyl methacrylate
• 2-hydroxymethyl-9-methyl-6-(1-methylethyl)-1,4-dioxa
• 2-isopropyl-2-(1-methylbutyl)-1,3-dimethoxypropane
• 2-isopropyl-4-( N -methyl)aminomethylthiazole
• 2-methoxypropanol
• 2-methyl- m -phenylene diisocyanate
• 2-methyl-4-(1,1-dimethylethyl)-6-(1-methyl-pentadecy
• 2-methyl-5-phenylpentanol
• 2-methylbutan-2-ol
• 2-methylpentane-2,4-diol
• 2-methylpropan-1-ol
• 2-methylpropyl 2-hydroxy-2-methylbut-3-enoate
• 3,7-dimethyloctanenitrile
• 3-(4-chlorophenyl)-1,1-dimethyluronium trichloroacet
• 3-butoxypropan-2-ol
• 3-chloro-2-(isopropylthio)aniline
• 3-chloropropene
• 3-hydroxy-1,1-dimethylbutyl 2-ethyl-2-methylheptanep
• 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyan
• 3-propanolide
• 3-tridecyloxy-propyl-ammonium 9-octadecenoate
• 3a,4,7,7a-tetrahydro-4,7-methanoindene
• 4,4'-methylenedi(cyclohexyl isocyanate)
• 4,4'-methylenediphenyl diisocyanate
• 4,8,12-trimethyltrideca-3,7,11-trienoic acid, mixed
• 4-(1(or 4 or 5 or 6)-methyl-8,9,10-trinorborn-5-en-2
• 4-(3,4-dichlorophenylazo)-2,6-di- sec -butyl-phenol
• 4-(4-nitrophenylazo)-2,6-di- sec -butyl-phenol
• 4-[(3-hydroxypropyl)amino]-3-nitrophenol
• 4-[3-(diethoxymethylsilylpropoxy)-2,2,6,6-tetramethy
• 4-bromo-2-chlorofluorobenzene
• 4-chloro-3,5-dimethylphenol
• 4-isocyanatosulphonyltoluene
• 4-methyl-8-methylenetricyclo[3.3.1.1 3,7 ]dec-2-yl a
• 4-methyl-8-methylenetricyclo[3.3.1.1 3,7 ]decan-2-ol
• 4-methylpyridine
• 4-phenylbut-1-ene
• 4-propylcyclohexanone
• 6-fluoro-2-methyl-3-(4-methylthiobenzyl)indene
• 7a-ethyl-3,5-bis(1-methylethyl)-2,3,4,5-tetrahydroox
• 8,9,10-trinorborn-2-yl acrylate
• 8,9-dinorborn-5-ene-2,3-dicarboxylic anhydride
• 9,9-bis(4-hydroxyphenyl)fluorene
• 9-vinylcarbazole
• [( p -tolyloxy)methyl]oxirane
• acetochlor (ISO)
• acibenzolar- S -methyl
• acifluorfen (ISO)
• acrylamide
• acrylonitrile
• allidochlor (ISO)
• allyl alcohol
• allyl glycidyl ether
• anilazine (ISO)
• azocyclotin (ISO)
• barium polysulphides
• benazolin (ISO)
• benomyl (ISO)
• benzene
• benzyl 2,4-dibromobutanoate
• benzyldimethyloctadecylammonium 3-nitrobenzenesulfon
• beryllium
• beryllium compounds with the exception of aluminium
• beryllium oxide
• biphenyl
• bis(1-methylethyl)-dimethoxysilane
• bis(piperidinothiocarbonyl) disulphide
• bis(α,α-dimethylbenzyl) peroxide
• bis-[4-(2,3-epoxipropoxi)phenyl]propane
• bis[(1-methylimidazol)-(2-ethyl-hexanoate)], zinc co
• bromelain, juice
• bromobenzene
• bromoform
• bromomethane
• bronopol (INN)
• butan-1-ol
• butanone oxime
• butroxydim (ISO)
• calcium 2,2,bis[(5-tetrapropylene-2-hydroxy)phenyl]e
• calcium polysulphides
• calcium sulphide
• camphechlor (ISO)
• carbon disulphide
• chloral hydrate
• chlorfenson (ISO)
• chlorine
• chlorobenzene
• chloroform
• chloroprene (stabilised)
• chlorphonium chloride (ISO)
• chymotrypsin
• citral
• copper sulphate
• crotonaldehyde
• cyclohexane
• cyclohexanol
• cyclohexyl acrylate
• cyclohexyldimethoxymethylsilane
• cyclopentanone
• cypermethrin cis/trans +/-80/20
• dalapon
• di- n -butyl ether
• di- tert -(C 12 – 14 )-alkylammonium 2-benzothiazoly
• diammonium peroxodisulphate
• diammonium tetrachloroplatinate
• dichlone (ISO)
• dichlorprop (ISO)
• dichlorprop-P (ISO)
• dicofol (ISO)
• dicyclopentyldimethoxysilane
• diethylcarbamoyl chloride
• diethyltoluamide (ISO): N,N-diethyl-m-toluamide
• dimercury dichloride
• dimethylcarbamoyl chloride
• dimethyldichlorosilane
• dinocap (ISO)
• dipentene
• dipotassium peroxodisulphate
• dipotassium tetrachloroplatinate
• diquat dibromide
• disodium tetrachloroplatinate
• disul (ISO)
• ditalimfos (ISO)
• dithallium sulphate
• DNOC (ISO)
• dodine(ISO)
• E -ethyl-4-oxo-4-phenylcrotonate
• endothal (ISO)
• endothal-sodium (ISO)
• ethyl 2-carboxy-3-(2-thienyl)propionate
• ethyl 2-cyanoacrylate
• ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate
• ethyl acrylate
• ethyl methacrylate
• ethyl trans -2,2,6-trimethylcyclohexanecarboxylate
• ethyl-2-chloro-2,2-diphenylacetate
• fatty acids, tall-oil, reaction products with iminod
• fenbutatin oxide (ISO)
• fenoprop (ISO)
• fenpropimorph (ISO)
• fentin acetate (ISO)
• fentin hydroxide (ISO)
• ferbam (ISO)
• ficin
• flumetralin (ISO)
• fluquinconazole (ISO)
• furan
• furathiocarb (ISO)
• glyoxal…%
• guaiacol
• guanidinium chloride
• guazatine (ISO)
• heptane
• hexamethylene diacrylate
• hexamethylene-di-isocyanate
• hexane (containing < 5 % n -hexane (203-777-6))
• hexyl acrylate
• hydroxylamine … % [> 55 % in aqueous solution]
• hydroxylammonium chloride
• isobutyl 3,4-epoxybutyrate
• isobutyl acrylate
• isobutyl methacrylate
• isobutylisopropyldimethoxysilane
• isooctyl acrylate
• isopropyl chloroacetate
• lead(II) methanesulphonate
• m -bis(2,3-epoxypropoxy)benzene
• magnesium bis(( R )-2-(2,4-dichlorophenoxy)propionat
• maleic acid
• MCPA (ISO)
• mecoprop (ISO)
• mecrilate
• methyl 2-benzylidene-3-oxobutyrate
• methyl 4-bromomethyl-3-methoxybenzoate
• methyl acrylate
• methyl chloroacetate
• methyl iodide
• methyl isocyanate
• methyl methacrylate
• methylcyclohexane
• methyltriphenylphosphonium chloride
• mixed linear and branched C 14-15 alcohols ethoxylat
• mono-methylamine
• mono[2-(dimethylamino)ethyl]monohydrogen-2-(hexadec-
• monoalkyl or monoaryl or monoalkyaryl esters of meth
• monoalkylor monoaryl or monoalkylaryl esters of acry
• morfamquat (ISO)
• morfamquat dichloride
• morpholine-4-carbonyl chloride
• N -2-naphthylaniline
• n -butyl acrylate
• n -butyl methacrylate
• N -hexadecyl(or octadecyl)- N -hexadecyl (or octadec
• n -hexane
• N, N -dimethylanilinium tetrakis(pentafluorophenyl)b
• N, N' -(2,2-dimethylpropylidene)hexamethylenediamine
• N-methyl-2-pyrrolidone
• naled (ISO)
• nickel carbonate
• nickel dihydroxide
• nickel sulfate
• o -xylene
• octane
• octasodium 2-(8-(4-chloro-6-(3-((4-chloro-6-(3,6-dis
• oxirane, mono[(C 12 – 14 -alkyloxy)methyl] derivs.
• oxydiethylene bis(chloroformate)
• p -benzoquinone
• p -toluenesulphonic acid (containing a maximum of 5
• papain
• paraquat dichloride
• pentachlorophenol
• pentaerythritol tetraacrylate
• pentaerythritol triacrylate
• penthachloronaphthalene
• pepsin A
• phenyl glycidyl ether
• phenylhydrazine
• phthalic anhydride
• potassium 2-(2,4-dichlorophenoxy)-( R )-propionate
• potassium chromate
• propanal
• propargite (ISO)
• proteases with the exception of those specified else
• proteinase, microbial neutral
• proxan-sodium (ISO)
• pyridate (ISO)
• reaction mass (ratio not known) of: ammonium 1-C 14
• reaction mass of 2-acryloyloxyethyl hydrogen cyclohe
• reaction mass of C 12-14 – tert -alkylammonium diphe
• reaction mass of dodecyl 3-(2,2,4,4-tetramethyl-21-o
• reaction mass of isomers of: methyldiphenylmethane
• reaction mass of: (1'α, 3'α, 6'α)-2,2,3' ,7', 7'-pen
• reaction mass of: (3-methoxy)propylammonium/[tris-(2
• reaction mass of: 2,2'-[[(2-hydroxyethyl)imino]bis(m
• reaction mass of: 2-chloro-5- sec -tetradecylhydroqu
• reaction mass of: 4 diastereoisomers of 2,7-dimethyl
• reaction mass of: 4-(2,2,3-trimethylcyclopent-3-en-1
• reaction mass of: [1-(methoxymethyl)-2-(C 12 -alkoxy
• reaction mass of: ammonium-1,2-bis(hexyloxycarbonyl)
• reaction mass of: diastereoisomers of 1-(1-hydroxyet
• reaction mass of: dicalcium (bis(2-hydroxy-5-tetra-p
• reaction mass of: dodecanoic acid (35-40 %)
• reaction mass of: ethyl exo -tricyclo[5.2.1.02,6]dec
• reaction mass of: tetradecanoic acid
• reaction mass of: tetradecanoic acid (42,5-47,5 %)
• reaction mass of: trans -(2 R )-5-acetoxy-1,3-oxathi
• reaction product of ammonium molybdate and C 12 -C 2
• Reaction product of: 1,2,3-propanetricarboxylic acid
• Reaction product of: polyethylene-polyamine-(C 16 -C
• reaction product: bisphenol-A-(epichlorhydrin)
• rennin
• resorcinol
• sabadilla (ISO)
• salts and esters of 2,4,5-T
• salts of mecoprop
• silicon tetrachloride
• sodium ( R )-2-(2,4-dichlorophenoxy)propionate
• sodium 2-biphenylate
• sodium 3,5-bis(3-(2,4-di- tert -pentylphenoxy)propyl
• sodium fluoride
• sodium salt of chloroacetic acid
• sodiumpentachlorophenolate
• spiroxamine (ISO)
• styrene
• styrene-4-sulfonyl chloride
• subtilisin
• sulphamidic acid
• sulphanilic acid
• tau-fluvalinate (ISO)
• tert -butyl acrylate
• tert -butyl methyl ether
• tert -butyl α, α-dimethylbenzyl peroxide
• tetrachloro- p -benzoquinone
• tetrahydrofuran-2,5-diyldimethanol
• tetrahydrothiophene
• tetrasodium 5-benzamido-3-(5-(4-fluoro-6-(1-sulphona
• thioacetamide
• thiocarbonyl chloride
• thionyl chloride, reaction products with 1,3,4-thiad
• thiram (ISO)
• toluene
• tolylfluanid (ISO)
• trans -4-cyclohexyl-L-proline monohydrochloride
• tributyl phosphate
• tributyltin compounds, with the exception of those s
• trichloro(methyl)silane
• trichloroethylene
• trichloronitromethane
• triclosan
• tridemorph (ISO)
• trioctylstannane
• trioctyltin compounds, with the exception of those s
• triphenyl phosphite
• trypsin
• turpentine, oil
• zinc 2-hydroxy-5-C 13 – 18 alkylbenzoate
• zinc bis(dibutyldithiocarbamate)
• zinc bis(diethyldithiocarbamate)
• α, α, α,4-tetrachlorotoluene
• α, α, α-trichlorotoluene
• α, α-dichlorotoluene
• α-bromotoluene
• α-chlorotoluene
• ε-caprolactam

Obblighi pratici

Se un prodotto contiene una sostanza di questa classe sopra le soglie pertinenti, la classificazione si riflette su etichetta CLP (pittogramma, avvertenza, indicazioni H, consigli P), scheda dati di sicurezza (sezioni 2 e 15), imballaggio ed eventuale notifica al centro antiveleni. Per le miscele il contributo dipende dalla concentrazione e da eventuali limiti specifici o fattori M.

Altre classi di pericolo salute

Il CLP raggruppa le classi in pericoli fisici, per la salute e per l'ambiente. Altre classi del gruppo «salute»:

• Tossicità acuta (Acute Tox.)
• Corrosione della pelle (Skin Corr.)
• Gravi lesioni oculari (Eye Dam.)
• Irritazione oculare (Eye Irrit.)
• Sensibilizzazione respiratoria (Resp. Sens.)
• Sensibilizzazione cutanea (Skin Sens.)
• Mutagenicità sulle cellule germinali (Muta.)
• Cancerogenicità (Carc.)
• Tossicità per la riproduzione (Repr.)
• Effetti sull’allattamento o attraverso l’allattamento (Lact.)
• Tossicità specifica per organi bersaglio – esposizione singola (STOT SE)
• Tossicità specifica per organi bersaglio – esposizione ripetuta (STOT RE)
• Pericolo in caso di aspirazione (Asp. Tox.)

Fonti

Classe e categorie secondo l'Allegato I e l'Allegato VI del Regolamento (CE) n. 1272/2008 (CLP). Gli elenchi di sostanze derivano dalla Tabella 3.1 dell'Allegato VI; verifica sempre la versione consolidata vigente e l'inventario C&L dell'ECHA.

Domande frequenti

Come faccio a sapere se una sostanza rientra in questa classe?

Si controlla la sua classificazione: nelle schede per sostanza trovi i codici di classe e categoria di pericolo tratti dall'Allegato VI del CLP, oppure si applica l'autoclassificazione sulla base dei dati disponibili.

Questa classe richiede un pittogramma in etichetta?

Sì, quando previsto dalla categoria: in etichetta CLP vanno riportati pittogramma, avvertenza, indicazioni di pericolo (H) e consigli di prudenza (P) coerenti con la classificazione.

Dove ritrovo l'elenco completo delle sostanze irritazione cutanea?

In questa pagina trovi gli esempi collegati alle schede; l'elenco completo è nell'archivio delle schede CLP per sostanza.

La classificazione può cambiare nel tempo?

Sì: gli ATP (adeguamenti al progresso tecnico) aggiornano l'Allegato VI. Verifica sempre la versione consolidata vigente e l'inventario C&L dell'ECHA.